Methodological aspects of the problem of spontaneous self-organization of systems having various origins are considered: uncertainty and ordering in their evolution, expediency of the evolution, and regular tending of the systems to equilibrium. The general equation of regularity is suggested. The regularity can manifest itself in formation of different systems like planets, soils, river floodplains, sea and lake shores, as well as biological, social-economic, and technical ones. Self-regulation peculiarities of systems of various origins are analyzed.