A review of investigations performed by researchers of the Institute of Atmospheric Optics of the SB RAS in the region of Lake Baykal is given, Starting from the formulated problem, the emphasis is on an analysis of the aircraft-laboratory application to salvaging of the Baykal environment. It is demonstrated that the aircraft-laboratory, capable of investigating the atmosphere on a regional scale, is the most important means for pursuance of integrated experiments, because its potentialities are adequate to scales of the examined phenomena that should be well understood to study correctly the ecological problems.