The numerical results on modeling the reconstruction of aerosol microstructure parameters divided into particle size fractions are presented. Solution of the inverse problem is based on the description of aerosol microstructure using integral distributions. In the case of submicron and coarse aerosol fractions, the developed method allows an estimate of the volume packing factor to be obtained with a 10% error; the average particle radius can be reconstructed accurate to 0.02-0.06 μm.