The paper summarizes the results of investigations and basic research carried out at the Institute of Optical Monitoring, SB RAS, over 30-year period. These investigations were aimed at the development of instruments and technologies for laser and acoustic sensing of the environment that might have promises from the viewpoint of remoteness and efficiency when determining profiles of both aerosol pollution and meteorological quantities, as well as monitoring spatiotemporal variations of their fields. The ground-based, airborne, and space-based lidars created at the Institute and intended for sensing the atmosphere and underlying surface are described. The design and application technologies are described as well. The investigation in acoustic sensing of the atmospheric boundary layer and achievements in creation of new instruments and sensing techniques are presented. The results of application of these instruments and acoustic sensing techniques to monitoring the atmospheric boundary layer and sound propagation inside this layer are presented.